In 1993, while Mark Latham was Mayor of Liverpool, Casula Powerhouse, as it had then become known, was allocated funding in council budgets for the very first time. An ambitious development took place, and the Centre opened its doors in 1994.

Situated on land traditionally owned by the Cabrogal Clan of the Darug Nation, Casula Powerhouse Arts Centre is a multi-disciplinary arts centre that has six galleries (with changing exhibitions produced and presented by Casula Powerhouse), a 326-seat theatre, artist studios, Clayhouse Ceramics Studio, live-in facilities for artists, internal and external public artworks, collection storage facility, retail areas including café and bar, and green open spaces. Casula Powerhouse Arts Centre runs a multi-disciplinary arts program that includes exhibitions, theatre, live music, dance, workshops, seminars and education programs.